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Alexan (Spironolactone)

Alexan is the generic form of the brand-name drug Alexan, a prescription diuretic drug. The drug is used to treat a condition called primary hyperaldosteronism, in which the body produces excess amounts of the hormone aldosterone, which regulates your body's sodium and water levels. Alexan helps restore a healthy balance of sodium and potassium in your body.

Other names for this medication:
Spironolactone, Aldactone, Aldactazide, Aldactazine, Aldazida, Aldazide, Aldozone, Alexan, Alizar, Carpiaton, Espirone, Espironolactona, Expal, Kespirona, Lanx, Letonal, Osiren, Osyrol, Practon, Prilactone, Spiractin, Spiresis, Spirix, Spiroctan, Spirolang, Spirolon, Spiron, Spirono, Spironolacton, Spironolactona, Spironolakton, Spironolattone, Spirotone, Verospiron, Xenalon,

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Alexan is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Alexan is also used to lessen the need for hospitalization for heart failure.

Alexan is also used to diagnose and treat hyperaldosteronism, a condition in which the adrenal gland produces too much hormone called aldosterone. This medicine may also be used to treat fluid retention (edema) in patients with congestive heart failure, liver cirrhosis, or a kidney disorder called nephrotic syndrome.

Alexan is a potassium-sparing diuretic (water pill). It prevents your body from absorbing too much salt and keeps your potassium levels from getting too low. This medicine is also used to treat or prevent hypokalemia (low potassium levels in the blood).

This medicine is available only with your doctor’s prescription.

This product is available in the following dosage forms:

  • Tablet
  • Suspension

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Formation of gapless Fermi arcs and fingerprints of order in the pseudogap state of cuprate superconductors. While they cause genetic damage and are cytotoxic, they also activate cellular pathways which alter gene expression, growth, and differentiation. Additional data sources included bibliographies of articles identified on MEDLINE, bibliographies in textbooks on percutaneous coronary interventions, and preliminary data presented at recent national and international cardiology conferences. Surfactant treatment in the neonate with severe respiratory distress syndrome. MAb PB1.3 significantly prevented both the pulmonary accumulation of leukocytes and subsequent pulmonary vascular injury.

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Chiral symmetry breaking during crystallization: an advection-mediated nonlinear autocatalytic process. On the basis of their results the authors consider the determination of fructose-amine level in addition to the profile-control informative and well applicable in the diabetological care. As portal blood flow increases, collateral flow increases and is nearly totally shunted in the systemic circulation.

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Meaning-making following spinal cord injury: Individual differences and within-person change. The Ilizarov technique with bone segment extension is effective in treating tibial infected nonunion with large bone defects. Prospective, controlled study among 74 consecutive HPV-infected heterosexual couples seeking their first medical intervention for sexually transmitted infections. If VPO1 mediates ApoE oxidation and affects the lipid metabolism remains to be elucidated. Endoluminal stent-graft relining of visceral artery bypass grafts to treat perigraft seroma.

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Our results suggest that a normal FEV(1)/VC ratio does not exclude airway obstruction. Recent studies have suggested that glycosphingolipid (GSL)-cholesterol microdomains in cell membranes may function as platforms for the attachment of lipid-modified proteins, such as glycosylphosphatidylinositol (GPI)-anchored proteins and src-family tyrosine kinases. Between January 2008 and August 2012, 95 patients with severe AR who underwent OSITS at the Department of Otolaryngology, Hyogo College of Medicine, were retrospectively analyzed. Dentin and osteodentin matrix formation in apicoectomized replanted incisors in cats. A comparative role of alveolar macrophages and polymorphonuclear cells against infection with Candida albicans.

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Moreover, the survival time of mice with endotoxic shock was increased in the presence of NAC. An early outward conductance modulates the firing latency and frequency of neostriatal neurons of the rat brain. However, despite the fact that it contains many predicted amphipathic alpha-helical domains, relatively little is known about its tertiary structure. The ability to identify the characteristics of patients with tuberculous and non-tuberculous mycobacteria may be helpful in identifying before treatment those patients more likely to have non-tuberculous infection.

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In this context we investigated the sensitivity of the rate ratio estimates to the choice of the hyperprior via a simulation study. Postischemic administration of a potent PTEN inhibitor reduces spontaneous lung infection following experimental stroke. Histological examination demonstrated that cyst wall was composed of the well-vascularized fibrous connective tissue with some inflammatory changes. This can promote tumor process, because maximum changes in hemopoietic cells occur during advanced stage of the disease.

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Furthermore, the nucleotides of the same region in the ureB gene were directly sequenced and compared. The findings suggest that the critical determinant of hip fracture risk in relation to the acid-base effects of diet is the net load of acid in the diet, when the intake of both acid and base precursors is considered.

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Resection in the proliferative phase should be considered to prevent complications associated with delayed treatment. Advance prediction of hypotension at cesarean delivery under spinal anesthesia. Characterization of a hyaluronic acid-Arg-Gly-Asp peptide cell attachment matrix. Confocal laser microscopy showed that the antigens recognised by the mAbs were located on the surface/cytoplasm, central part, and/or anterior end of B. Modified United States Public Health Services criteria were used for the clinical evaluation.

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We postulated that the haematoma provided a source of chondrogenic cells for endochondral ossification during fracture healing and preservation of the cells contributed to biological fracture healing. Dynamic light scattering (DLS) and RNA absorbance were employed to determine the extent of exosome aggregation and electroextraction post electroporation in TPM compared to common PBS pulse media or sucrose pulse media (SPM). The order of effectiveness of a group of pyridinones found for iron removal from ferritin molecules in solution differs from that obtained with hepatocytes in culture or with whole animals, where membrane solubility and other factors may modulate the response. A total of 430 non-related Chinese Hans were enrolled, which included 145 patients with idiopathic membranous nephropathy (IMN), 53 patients with secondary MN and 232 normal controls (NC).

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In computer science, the notion of a domain ontology--a formal specification of the concepts and of the relationships among concepts that characterize an application are a--has received considerable attention. A general model for the absorption of ultrasound by biological tissues and experimental verification. Comprehensive analysis of oncogenic mutations in lung squamous cell carcinoma with minor glandular component. For each line the residual homologous synaptic ability of the recombinant chromosome in its proximal wheat and distal alien portion was estimated through meiotic analyses. We sought to determine whether limb preservation efforts in this population could be justified from a patient-centered, cost-effectiveness perspective.

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We explored whether this can be achieved by a measure incorporating both early and late measures of outcome (e.g. Among iron depleted anaemic patients, iron deficiency anaemia was identified using the response to iron supplementation. The characteristics of sevoflurane as evaluated in the present study make it a suitable anesthetic in pediatric outpatient surgery even in the presence of mild URI. The role of extracellular phospholipase as a potential virulence factor in pathogenic fungi, including Candida albicans, Cryptococcus neoformans, and Aspergillus, has gained credence recently. The patient was aware that aspects of his performance were impaired, but he was unable to state why--a dissociation between declarative and procedural knowledge.

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IDDM patients had a high excess mortality in comparison with the general population. Relation between chronic disease of the appendix and hyperglycemic conditions or diabetes respectively The interpretation and estimation of the summary vaccine efficacy were discussed in light of other two models of vaccine action: the leaky and all-or-nothing model. Recent data suggests that the newly developed flexible 19 gauge needle can also procure core tissue and has easy maneuverability when navigating the transduodenal route.

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In the first case, these latter considerations were not fully observed and in the third postoperative week, arterial thrombosis with loss of the transfer developed, following an infection. Moreover, target cells were found to secrete soluble variants of BAG-6 and release BAG-6 on the surface of exosomes, which inhibit or activate NK cell cytotoxicity, respectively. Abnormalities of mechanotransduction leading to aberrant chondrocyte activity in diseased articular cartilage may be important in the progression of OA. We describe 5 cases of mucoepidermoid carcinoma (MEC) involving Warthin tumor (WT) of the parotid gland.

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Obesity and/or psychopathological disorders of parents represent risk factors for childhood obesity. The early lamellar keratoplasty groups recovered better than in middle and later lamellar keratoplasty groups.

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Since Myc overexpression has been associated with reduced expression of beta1 and beta2 integrins, we have investigated the role of c-Myc on CD11a and CD11c transcription. Ocular drug delivery has thus become one of the main challenges of modern ophthalmology. Involved in such control of muscle stem cell fate in embryos are members of the Pitx gene family of bicoid-class homeodomain proteins. The responses of single units in the ventral cochlear nucleus of the guinea pig to damped and ramped sinusoids. Treatment is aimed at altering the abnormal mechanical interaction of the upper lid and superior corneal limbus.

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Other recent studies have revealed an miRNA response to either bacterial pathogens or commensal bacteria. The impact of airways obstruction on quality of life does not decrease with advancing age.

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Various techniques including hypotensive anaesthesia have been described, but the control of intraoperative bleeding does not rely on a single particular technique, but a series of well-designed interventions that result in optimal conditions. These findings bring further support to the nociceptive nature of the afferent fibers running into the oculomotor nerve.

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No compound-related alterations in sperm motion or density were detected in the offspring. Occurrence of gaseous and particulate polycyclic aromatic hydrocarbons in the urban atmosphere: study of sources and ambient temperature effect on the gas/particle concentration and distribution. Effect of guinea pig and rat serum on Diplococcus pneumoniae type I. These studies showed high prevalence of vitamin D deficiency in Asian countries.

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As MZR is reported to be less toxic than other cytotoxic drugs, it is frequently used in Japan in the treatment of adult patients with rheumatoid arthritis or lupus nephritis. A dental hygienist from our clinic visits and offers oral and dental health (oral care) and oral and dental support (oral rehabilitation) to home patients as part of a care plan with home care nurses. The results of the control experiment confirm the hypothesis that perceptual judgement and visuo-motor transformation are two separate processes during which the same object attributes are independently analysed.

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The paper describes a case of metastatic glioblastoma in a 64-year-old woman who died in the early postoperative period after tumor removal. Artemisinin resistance, a long parasite clearance half-life in response to artemisinin, has been described in patients with Plasmodium falciparum malaria in southeast Asia. Vocal fold augmentation with injectable calcium hydroxylapatite: short-term results. Hypertensive rats (SHRSP, SHRSR) were originally produced from WKY.

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Low-dose aspirin alone did not significantly increase ulcer incidence. A retrospective bi-centric study included all patients with resected BMs from primary colorectal adenocarcinoma from 1998 to 2009.

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By 24-36 h, the number of total lymphocytes and the nucleologram had returned to baseline values. Considering the function of RNase L and the pleiotropic effects of mutations associated with cancer, we sought to investigate whether the RNASEL G1385A variant is a risk factor for breast cancer. The length of the pedicel is positively correlated with deutonymph body size between species, but not within species. A unique strain of Leptospira isolated from a patient with pulmonary haemorrhages in the Andaman Islands: a proposal of serovar portblairi of serogroup Sehgali.

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The concentration ranges of the two- to six-component mixtures are from 50 ppm to 100 ppb. Basal-like breast cancer (BLBC) is an aggressive breast cancer subtype, frequently associated with PI3K pathway activation. Evidence regarding the effects of exercise after vertebral fracture, particularly for men, is scarce. Although we anticipated clear-cut responses to dry-season intensity, the finding that many species have pronounced associations with either high or low phosphorus reveals a previously unquantified role for this nutrient in limiting tropical tree distributions.

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55 fractures were operated on with the MSP, and 52 with the dynamic hip screw (DHS) with or without a trochanteric stabilizing plate (TSP) or with the dynamic condylar screw (DCS). Mediastinal abscess after endobronchial ultrasound-guided transbronchial needle aspiration: a case report and literature review. We concluded that SDLAGL is involved in the shift of telomerase-positive, proliferating cells to telomerase-negative, non-proliferating cells. After x-ray examination, which showed a large osteolytic lesion, mandibular CT revealed a solid expanding mass. We report the results of our experience of spinal cord function monitoring by measuring motor evoked potentials (MEP) during endovascular treatment of TAAA type II and III.

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Procedures necessary for fabricating a surgical guide are explained for placing an ITI angled implant. The etiology is multifactorial and includes hormonal and molecular factors. The influence of PSA-RNA yield on the analysis of expressed prostatic secretions (EPS) for prostate cancer diagnosis. Females were also found to have more concern and empathy for others and a better developed superego. To evaluate the ethnic differences in the home physical activity and screen time environment of preschoolers enrolled in Head Start.

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Objectives and practice in so-called specific therapy of schistosomiasis mansoni The objective of this study was to determine the success rate and complications of using the percutaneous approach of the external jugular vein (EJV) for placement of a totally implantable venous-access port (TIVAP) with a preoperative estimate of the detailed anatomical orientation of the cervical venous plexus using computed tomography venography (CT-V). One of the hallmark effects of trehalose, a disaccharide consisting of two alpha-glucose units, is as a chemical chaperone with anti-aggregation activity.

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Measuring the benefit of performance improvement and decision support. Thapsigargin, an activator of the ER stress response, also inhibits protein synthesis and activates proteolysis of SREBP. The oxidative stress indicators (malondialdehyde - MDA, protein oxidation - POX, phospholipase A2 - PLA2 activity) and the oxidative status (superoxide dismutase (SOD) and catalase activities) were determined in the blood samples taken at the pre-hemodialysis treatment, at baseline (0 months) and after four months. The iliac arterio-venous difference of hypoxanthine and lactate markedly increased immediately post-ischaemia, while the phosphocreatine difference decreased.

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Grounded in methodologies developed by the aviation industry, SBT exceeds traditional didactic and apprenticeship models in terms of speed of learning, amount of information retained, and capability for deliberate practice. Development and validation of a portable platform for deploying decision-support algorithms in prehospital settings.

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Purification of rat adrenocortical actin and its use in an immunoprecipitation assay to quantitate cellular actin. Both hours of employment and drinking may be products of weak bonds to school and family. Magnetic resonance imaging (MRI) is now considered the imaging modality of choice for the evaluation of the larynx. These methods could be a useful supplement to sentinel node biopsy. The possible significance of volatile fatty acids in frass is discussed.

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The closing thoughts on the therapeutic implications from the presented results include suggestions on methodical approaches more suitable for children and a reflected therapeutic attitude (transparency, participation, respect) towards children. A wide variety of artifacts is routinely encountered on MR images. This study found that knowledge was improved among caregivers following the implementation of formal oral hygiene training. On both equity and efficiency grounds, discounts for actual bad debts are shown to be inappropriate.

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Despite evidence that greater US Medicare spending is not associated with better quality of care at a regional level, recent studies suggest that greater hospital spending is associated with lower risk-adjusted mortality. Immunoreactive prokallikrein was associated into punctate clusters occupying the external surface of the neutrophil membrane and, after addition of exogenous zymogen, immunolabeling was enhanced four-fold. Probing the pore region of recombinant N-methyl-D-aspartate channels using external and internal magnesium block. Children who exhibit these features should be given high priority for TCD examination in the setting of limited resources. Prognostic value of isocitrate dehydrogenase 1, O6-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in Japanese malignant glioma patients.

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Here we examined the opening effect of KR-31378 on the KATP channel using patch clamp recording in neuroblastoma 2a (N2a) cells and investigated the neuroprotective effect of KR-31378 in organotypic hippocampal slice cultures exposed to oxygen/glucose deprivation. Both groups should be observed, especially in terms of the current focus on overweight children. The use of an automatic manually triggered device may improve ventilation efficiency and decrease the risk of pulmonary overdistention, while decreasing the ventilation rate. He showed a remarkable clinical response to treatment with acitretin, which resulted in prolonged remission of the disorder. Diet and nutrition in psoriasis: analysis of the National Health and Nutrition Examination Survey (NHANES) in the United States.

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Zinc 2-((2-(benzoimidazol-2-yl)quinolin-8-ylimino)methyl)phenolates: synthesis, characterization and photoluminescence behavior. The similarity of the responses of reptilian and mammalian cochleas to pharmacological intervention provides further evidence for a common mechanism of cochlear amplification. We analyze our approach by a simulation study and by application to a dataset of the genome of the bacterium Xylella fastidiosa. The aim of the day was for a panel of experts to evaluate the current evidence base in relation to either the beneficial or detrimental effects of orthodontic treatment on the gingival tissue.

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However, the sensitivity was restored in the Px-core mice within 12 weeks after the injection. To highlight the development of psychotherapy in psycho-oncology, providing two illustrations. An impaired sensorimotor gating, measured by prepulse inhibition (PPI) of the acoustic startle response, was observed following a hippocampal afterdischarge (AD) or systemic injection of PCP and was accompanied with an increase in hippocampal gamma waves (30-70 Hz). Further metabolic and pharmacokinetic studies are required in order to determine whether neoglycolipid conjugates of foscarnet can find a use as drug targeting forms of foscarnet. Thermodynamic parameters like change of enthalpy (delta H) and free energy (delta G) of the process were evaluated.

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However these conclusions relate to techniques and drugs which are now rarely used during general anaesthesia for hip fracture surgery. A possible explanation for their specific effects on glucose transport. The prostatic weights in Groups V, VI and VII increased significantly in comparison with the weight in Group IV. Experimental evidence for an enzymatic basis for itching in man. The advantages of this method, besides its simplicity, are that it can determine the charge of, e.g., a protein in a free-fluid phase and that the pH and ionic composition of the bathing fluid can be varied over a broad range.

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This model suggests that an explanation for observed characters of proteins such as the diminution of function by substitutions distant from the active site, the existence of protein folds (superfolds) that can perform several functions based on one architecture, and structural and functional resilience to destabilizing substitutions might derive from their inherent network-like structure. Some investigators recruited patients because of anti-HCV positivity and elevated transaminases and found cirrhosis only at histology, whereas others recruited patients because cirrhosis had been diagnosed.

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Serum progesterone concentration in the treated cows decreased progressively and were 0.4 to 1.5 ng/ml at the time of premature calving. Significance of certain laboratory investigations in evaluation of therapeutic effect in the treatment of chronic gastritis with secretory insufficiency Studies of overtime have pointed to fatigue as a potential factor producing, for example, a three-fold increase in accident rate after 16 h of work, increases in back injuries, hospital outbreaks of bacterial infection, or nuclear-power plant safety compromises.

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The instruments used were the Child Problem Behavior list by Hong (1986), the Body Cathexis Scale by Secord and Jourard(1953), and the Beck Depression Inventory by Beck(1978). A double-blind study with this method suggests that ibuprofen and caffeine administered together provides greater analgesic effectiveness than either component alone. Association of hypertension with stroke recurrence depends on ischemic stroke subtype.

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Enantioselective protonation of alkenyl trifluoroacetates catalyzed lamotrigine pregnancy autism test by chiral tin methoxide. The Bristol Female Lower Urinary Tract Symptoms questionnaire: development and psychometric testing. To study the antagonistic effect of oleanolic acid (OA) on anaphylactic shock in guinea-pigs sensitized with 6-aminopenicillanic acid (APA)-protein. Production and purification of polymerization-competent HIV-1 capsid protein p24 (CA) in NiCo21(DE3) Escherichia coli.

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Designed cefuroxime axetil formulations had good qualities and could be added as a new product to Iran drug marketing. The findings are discussed in the light of current relevant research, and implications for management of depressed mood in stroke fulcro insurance of ga llc patients are suggested. Increased emphasis on screening for high risk sexual behaviours, testing for T vaginalis, and risk reduction counselling is necessary for all HIV-infected women. Shiga toxins (Stx) are the main virulence factors in enterohemorrhagic Escherichia coli (EHEC) infections, causing diarrhea and hemolytic uremic syndrome (HUS).

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Coping and emotion lansoprazole dosage for barrett's esophagus regulation profiles as predictors of nonmedical prescription drug and illicit drug use among high-risk young adults. In patients with patent ductus arteriosus (PDA), transcatheter closure is the current procedure of choice. The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists. The study of symbiotic nitrogen transfer in soil has largely focused on nitrogen-fixing bacteria.

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A 17 years old female presented with multiple asymptomatic cutaneous cysts all over body, sparing the head and neck region. RADAR also includes an expandable listing of tissue-specific editing levels for each editing site, which will facilitate the assignment of biological functions to specific editing sites. An interleukin-1 lucon vs strasbourg region genotype is associated with fatal outcome of meningococcal disease.

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To examine the relationship of the DNA adduct-forming ability of these compounds eslicarbazepine vs oxcarbazepine bipolar with their physicochemical properties such as stable conformation and chemical reactivity, we carried out molecular mechanics, molecular dynamics, and quantum mechanics calculations for the two compounds. Protective effects of Pogostemon cablin Bentham water extract on inflammatory cytokine expression in TNBS-induced colitis in rats. Osteoplastic flap with obliteration: is this an ideal procedure for chronic frontal sinusitis?

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