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Parkan (Trihexyphenidyl)

Parkan increased wakefulness and decreased REM sleep while biperiden decreased REM sleep selectively. Ratings of anticholinergic symptoms and of feeling the effects of the drug, controlled for order effects, were significantly higher at week 4 of the Parkan trial than at week 4 of the placebo trial.

Other names for this medication:
Trihexyphenidyl, Artane, Benzhexol, Broflex, Cyclodol, Hexymer, Hipokinon, Pacitane, Pargitan, Parkan, Parkisan, Parkizol, Parkopan, Rodenal, Romparkin, Tonaril, Trihexifenidilo, Trihexy, Trihexyphen,

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Parkan is used along with other medications to treat the symptoms of Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance) and to control extrapyramidal symptoms (tremor, slurred speech) caused by certain medications. Parkan is in a class of medications called antimuscarinics. It works by relaxing muscles and nerve impulses that control the function of muscles.

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There are a number of pharmacological effects that are of uncertain clinical significance, such as blockade of calmodulin, sodium and calcium channels and alpha2-adrenoceptors in the central nervous system. It is demonstrated that the periodic potential of nearest-neighbor interaction allows one to obtain normal heat conductivity in an isolated one-dimensional chain with conserved momentum.

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mSPRITE images reconstructed from early FID samples suffer from reduced spatial resolution due to the limited extent of its corresponding k-space. This case is noteworthy because the patient exhibited an unusual combination of healed leprosy sequelae and active PKDL lesions, which caused a diagnostic dilemma. Hemichorea-hemiballism (HC-HB) is the most common of them all, and it is usually related to oportunistic toxoplasmosis of the basal ganglia.

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The formation and rupture of cerebral aneurysms has been controversial. In behavioral studies, Italian students showed faster word and non-word reading than English students. To investigate the relationship between T-wave inversions and left ventricular (LV) segmental hypertrophy and myocardial fibrosis assessed by cardiovascular magnetic resonance (CMR) in patients with non-apical hypertrophic cardiomyopathy (HCM).

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To determine the prevalence of myocardial damage in severe respiratory syncytial virus (RSV) disease as evident from elevated cardiac Troponin T (cTnT) levels. Optimizing autologous stem cell mobilization strategies to improve patient outcomes: consensus guidelines and recommendations. Exposure to Pb did not cause a significant decrease in biomass in either P. Surveillance of Legionella species in hospital water systems: the significance of detection method for environmental surveillance data. Awareness of this rare complication of PTU treatment may prevent the performance of unnecessary, expensive and possibly harmful diagnostic procedures.

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Posterior neocortical (visual cortex) lesions in the rat impair matching-to-place navigation in a swimming pool: a reevaluation of cortical contributions to spatial behavior using a new assessment of spatial versus nonspatial behavior. We evaluated upper cheek dentition of browsing Diceros bicornis and Rhinoceros sondaicus, mixed-feeding R.

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In 500 laparoscopic cholecystectomies we used a modified technique of cholecystcholangiography. Here, we demonstrate that all these proteins, except Hxt12, and additionally three members of the maltose transporter family (Agt1, Ydl247, Yjr160) are able to transport hexoses. Sample preparation is simple, involving either straight dilution for linctus formulations or simple dissolutions for pastilles. Medical history, including electrocardiographic and echocardiographic data, was analyzed.

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In this way, breaking of fine vessel ends as a result of mechanical overload is avoided. Metabolomic changes in follicular fluid induced by soy isoflavones administered to rats from weaning until sexual maturity. In this article three simple applications for microcomputers in the training program setting are explained. Acute carpal tunnel syndrome caused by hydroxyapatite crystals: a case report.

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pertussis-activated IL-12 or IL-23 production by dendritic cells. The 1-exp function as an alternative model of non-linear saturable kinetics. The information that ultimately remains available for retrieval may tend to be that which is reactivated during sleep. These case types represent a relevant part of the study population. The highest endothelialization rates in an early incubation period were found on films with microspores between 18 and 50 microns in diameter.

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What is common in Brazil can be a sporadic presentation in Europe. MtDNA gene genealogies and microsatellite-based clustering together revealed three divergent lineages of sinicus, corresponding to Central China, East China and the offshore Hainan Island. Targeting of chlorine E6 by EGF increasing its photodynamic activity in selective ways Single amino acid substitutions for each of these residues significantly decreased ribosome-binding efficiency. The paternalistic approach was generally accepted, moreover expected by the patients from the physicians.

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The reactivities of different alloantisera were analyzed statistically in pairwise comparisons. Reactive changes of the cultured cardiomyocytes were assessed by methods of light and electron microscopy.

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It was concluded that the extract may contain components that are mildly toxic to the liver and heart of rats after repeated daily oral administrations of 1,000 mg/kg body mass. Intracellular location of cysteine transport activity correlates with productive processing of antigen disulfide.

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These impairments are seen using ligands internalized by the non-specific process of fluid phase endocytosis as well as those internalized by coated pit endocytosis. The expression of a number of general splicing factors was studied. Some comments on the National Food Survey and comparison with the prewar Carnegie Survey. AEC2 were obtained by primary culture from 20-days fetal rat lung and hyperoxia-exposed cell model was established. Modification of the cutaneous muscular flap approach for lower blepharoplasty.

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In the literature, a few cases of fragile X syndrome associated with malignancies are described. Antiproliferative activity of liposome-encapsulated transforming growth factor-beta against MDA-MB-435 human breast carcinoma cells. The head and neck position influences the distances between the dorsal spinous processes of the vertebrae of equine thoracic spine on radiography. Low-power HeNe laser irradiation applied to a crushed injured sciatic nerve in the right leg in a bilaterally inflicted crush injury, significantly increased the compound action potential in the left nonirradiated leg as well.

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company broadens customer base for medical-surgical supplies and equipment. Using RT-PCR, AhR mRNA was shown to be expressed constitutively in the whole ovary of IHR with maximum down-regulation at 6 h after TCDD (20 microg/kg). The general applicability and usefulness of the method for the analysis of regime shifts is further demonstrated in the case of the mycobacterial switch to persistence for which experimental data are available. Quantum phase transition in an atomic bose gas with a feshbach resonance. Design of a photoreactive analogue of the Escherichia coli heat-stable enterotoxin STIb: use in identifying its receptor on rat brush border membranes.

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Health of shift workers may therefore improve when stress is reduced at times when the clock produces high stress sensitivity. Polymorphism complexity and handedness inversion in serum albumin amyloid fibrils. Placental lactogenic activity has been detected in primates (chimpanzee, orangutan), rodents (voles, Pinon mouse, guinea-pig, mara), and in numerous artiodactyls (llama, giraffe, several species of deer, antelope, gnu, gazelle, musk ox, cape buffalo, Barbary sheep, several sheep of the genus Ovis, goat, and cow).

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Periodic follow-up of patients with FMF MEFV mutations in subjects with acute-phase reactants may be useful in the prevention of morbidity. In this study, a coupling agent multilayer on glass was doped with trace levels of the dimethylaminonitrostilbene (DMANS) fluorophore. Our results show that the immunosuppressive effects and bone marrow toxicity of azathioprine are not a consequence of release of 6-MP alone, and with appropriate modification can be separated, an approach which may lead to less toxic immunosuppressive drugs. Further detailed analysis of Pgp topology will help to understand the fundamental mechanism of drug transport by Pgp. Chemotherapy has been shown to induce apoptosis in esophageal cancer.

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The risk and prognosis of cancer after hospitalisation for herpes zoster: a population-based follow-up study. A critical question for public health is whether the prion protein deposition reported in peripheral tissues from this MV individual correlates with infectivity. We are interested in the development of egg polarity and have characterized the localizations of several markers for egg polarity in normal metaphase II eggs and GV-intact oocytes.

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Light trapping and near-unity solar absorption in a three-dimensional photonic-crystal. Extracellular single-unit recording techniques were used to examine the firing characteristics of neurons in the medial septum/diagnol band of Broca complex (MS/DB) following injections of the 5-HT1A agonist, 8-OH-DPAT, into the median raphe nucleus (MRN) of urethane-anesthetized rats. Indications for t-ACC were severe sepsis requiring reoperation, abdominal compartment syndrome, abdominal wall tissue loss or a combination of these. More than a ten-fold content of bulky glycosylated hydroxylysine residues in type V collagen compared to that of type I might have a significant influence on both the intermolecular and interfibrillar interactions of the triple-helical domain of type V collagen molecule. Conversely, nuclei in both Kinesin and Dynein mutant embryos change direction more often and do not maintain the same leading edge when changing directions.

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