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When antigenically homogeneous, or mixed, populations were transmitted by tsetse flies to goats, the first peak parasitaemias arising in the goats were antigenic mixtures (up to 9 major, and several minor variants being recognized in some cases) from which the ingested variant was absent. We have used Epstein-Barr virus (EBV) episomes as a gene transfer system to study the role of promoter-proximal pausing and transcript elongation in c-fos expression. Autologous techniques for the reconstruction of pediatric microtia often result in suboptimal aesthetic outcomes and morbidity at the costal cartilage donor site.

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Nuclear run-off analysis established transcriptional up-regulation of PDGF-B chain in virus-inoculated macrophage cultures. GR substituted for the androgen receptor (AR) to activate a similar but distinguishable set of target genes and was necessary for maintenance of the resistant phenotype. Monitoring the mineralisation of bone nodules in vitro by space- and time-resolved Raman micro-spectroscopy.

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The main protoxin/activated toxin-binding glycolipid in the acidic fraction was designated band 1, the structure of which is at present unknown. Transverse sections of 6 microm were cut, immunohistochemically stained for NF 90, and counterstained by Sirius Red. A10 lesions produced a significant depletion of dopamine in the nucleus accumbens and cingulate cortex, but these effects were not significantly correlated with any measure of sexual behavior.

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Performance comparison of two novel combinative particle-size-reduction technologies. In conclusion, we have shown that S100A4 sensitizes osteosarcoma cells to IFN-gamma-mediated induction of apoptosis. The culture supernatant of cells transfected with these DNAs inhibited the migration of T cells and macrophages induced by MCP-1 and IP-10. BRAF mutation V600E (substitution Val600Glu) is a molecular signature for papillary thyroid carcinoma (PTC). Development of a new chemically modified carbon paste electrode for selective determination of urinary and serum oxalate concentration.

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Exogenous cholesterol, a clinically relevant countertreatment, failed to correct for the learning impairment produced by BM treatment. Congenital cheek teratoma with temporo-mandibular joint ankylosis managed with ultra-thin silicone sheet interpositional arthroplasty. Immobilized enzymes as biocatalysts have great potential both scientifically and industrially because of their technological and economic importance. The tendon excursion, toe motion, morphology of the sheath and tendon healing were studied 6 weeks after tendon repair.

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Efficacy of Deferasirox for the treatment of iron overload in Chinese thalassaemia major patients: results from a prospective, open-label, multicentre clinical trial. Tongue pressure data taken from healthy subjects during normal oral activities such as mastication, speech and swallowing are providing us with new ways of understanding the role of the tongue in craniofacial growth and function.

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O-methylated metabolite of 7,8-dihydroxyflavone activates TrkB receptor and displays antidepressant activity. Treatment of lower extremity diabetic ulcers typically includes surgical debridement of the wound and appropriate oral or intravenous antibiotics.

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Influence of resuspension on the fate of fecal indicator bacteria in large-scale flumes mimicking an oligotrophic river. A method for caging a target protein with steric regulator molecules was developed to enable simple, strict, light-induced control of protein activity. To assess the in vivo prothrombotic potential of rHuMGDF, a rabbit carotid artery model of cyclic flow reduction (CFR) was used.

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Usefulness of spasmolytics in the diagnosis and treatment of renal pain By light and electron microscopy it was shown that the tissue fragments had a differentiated epithelium at their surface throughout the culture period. Selective image blur is thus a potentially useful addition to computer-generated and cartoon images to enhance the impression of depth they convey. Complementary computed tomography is recommended, if ultrasonography cannot establish the diagnosis of jugular vein thrombosis or if the thrombosis involves the v. Residual fatigue in Guillain-Barre syndrome is related to axonal loss.

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This study investigated the effect of parental bereavement on cancer incidence and survival. After the discovery and initial characterization of Rickettsia felis in 1992 by Azad and cols, and the subsequent first description of a human case of infection in 1994, there have been two communications of human rickettsiosis cases caused by Rickettsia felis in Latin America. To compare the safety and effectiveness of treatment of forehead and glabellar lines with botulinum toxin A alone versus botulinum toxin A and filler. The coupling chemistry employed may have application in current attempts to effect binding of drugs to high molecular weight targeting antigens.

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Glial inhibition of nerve regeneration in the mature mammalian CNS. New drugs have recently been developed, through a better understanding of the mechanisms involved in the progression of prostate cancer, including castration-resistant ones (CRPC). Lack of modifying effects of environmental estrogenic compounds on the development of thyroid proliferative lesions in male rats pretreated with N-bis(2-hydroxypropyl)nitrosamine (DHPN). Gigantic clavicle osteochondroma with carotid compression as a rare cause of stroke. In this prospective phase II trial, patients were treated with three cycles of epirubicin, cisplatin, and capecitabine (ECX), followed by cetux-RT.

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We analyzed the CNS tissues of a young woman who died of a demyelinative disease, which was clinically and histopathologically diagnosed as acute multiple sclerosis, for active HHV-6 infection by immunohistochemical staining. Rearrangement of bioelectric activity of the brain during adaptation to chronic hypokinesia We now demonstrate that the GTPase involved in the regulation of cargo uptake is ARF, revealing a multi-functional role of this GTPase in COPI-mediated vesicular transport. Neutrophil elastase and the lung, with special reference to the pathogenesis of ARDS

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