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Auram (Oxcarbazepine)
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Oxcarbazepine

Auram is in a group of drugs called anticonvulsants, or antiepileptic drugs. It works by decreasing nerve impulses that cause seizures. Auram is used to treat partial seizures in adults and children who are at least 2 years old. Auram is like carbamazepine in its mechanisms of action and antiepileptic efficacy but has better tolerability and fewer interactions with other drugs. Most of the clinical development took place during the early 1990s, when it received approval in several countries. It was approved by the FDA in 1999. In 2003, the FDA approved Auram as a monotherapy in children 4 years or older with partial epilepsy.

Other names for this medication:
Oxcarbazepine, Trileptal, Actinum, Apydan, Auram, Aurene, Deprectal, Leptal, Oxcarbazepin, Oxcarbazepina, Oxetol, Oxicodal, Tolep,

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Auram comes as a tablet, an extended-release tablet, and a suspension (liquid) to take by mouth. The tablet and suspension are usually taken every 12 hours (twice a day) with or without food. The extended-release tablet is usually taken once a day on an empty stomach, 1 hour before or 2 hours after a meal. Take Auram at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Auram exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Shake the suspension well right before each use to mix the medication evenly. Use the oral dosing syringe that came with the medication to withdraw the right amount of suspension from the bottle. You can swallow the suspension straight from the syringe or you can mix it with a small glass of water and swallow the mixture. Wash the syringe with warm water and allow it to dry thoroughly after use.

Swallow the extended-release tablets whole with water or another liquid; do not split, chew, or crush them.

Your doctor will probably start you on a low dose of Auram and gradually increase your dose, not more often than once every 3 days. If you were taking another medication to treat your seizures and are switching to Auram, your doctor may gradually decrease your dose of the other medication while increasing your dose of Auram. Follow these directions carefully and ask your doctor if you are not sure how much medication you should take.

Auram may help control your seizures but will not cure your condition. Continue to take Auram even if you feel well. Do not stop taking Auram without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood. If you suddenly stop taking Auram, your seizures may get worse. Your doctor will probably decrease your dose gradually.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with Auram and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions. You can also visit the Food and Drug Administration (FDA) website (http://www.fda.gov/Drugs) or the manufacturer's website to obtain the Medication Guide.

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