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Expansia (Clopidogrel)
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Clopidogrel

Expansia is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Expansia is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial disease. It has been shown to be superior to aspirin in reducing cardiovascular outcomes in patients with cardiovascular disease and provides additional benefit to patients with acute coronary syndromes already taking aspirin. Expansia was granted FDA approval on 17 November 1997.

Other names for this medication:
Clopidogrel, Plavix, Anclog, Anlet, Antiplar, Artevil, Clavix, Clopicard, Clopilet, Clopivas, Deplatt, Diloxol, Duoplavin, Expansia, Farcet, Globel, Grepid, Iscover, Karum, Klopidogrel, Nabratin, Narutis, Nefazan, Noklot, Pidocar, Pidogrel, Pladex, Plagerine, Planor, Tisten, Troken, Trombex, Vaclo, Zyllt,

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Talohexal, Quantrum, Regan, Sildalis, Hipres, Levocine, Clindahexal, Noritate, Indobene, Proximax, Alicante, Ampliron, Neutop, Voxin, Clavamel, Tritace, Vocado, Procap, Ozepam, Melocin, Remoxin, Lancid, Gadopril, Birodogyl, Colcibra, Aponal, Espirone, Neurosine,

Expansia is used alone or together with aspirin to lessen the chance of a heart attack or stroke. It is given to patients who have already had a heart attack, severe chest pain, or a stroke, or to patients with other circulation problems that could cause a stroke or heart attack.

A heart attack or stroke may occur when a blood vessel is blocked by a blood clot. Expansia is a platelet inhibitor. It reduces the chance that a harmful blood clot will form by preventing platelets from clumping together in the blood. Expansia may also increase the chance of serious bleeding in some people.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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The major goal of surgical treatment in morbid obesity is to decrease morbidity and mortality associated with excess weight. A DNA nano-zipper built from double crossover structures is demonstrated in this work. It is shown that the devised concept of scatter correction significantly improves the results of MVCT- and dose reconstruction models, which is in turn essential for an exact online IMRT verification. Stabilizers that co-translationally improve the solubility and functional folding of human glucosamine 6-phosphate N-acetyltransferase have been identified and cumulative effects of stabilizers have been studied.

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Statistical models for estimating the genetic basis of repeated measures and other function-valued traits. Electrophysiological estimation of the actions of acetylcholinesterase inhibitors on acetylcholine receptor and cholinesterase in physically isolated Aplysia neurones. Fat mass and fat-free mass were measured with bioelectric impedance analysis (BIA). Despite the increased attention towards the problems associated with multiresistant bacteria, there are still major efforts needed for prevention and early treatment of sepsis with non-resistant bacteria. These results are consistent with neural models of boundary and surface formation which suggest that achromatic and chromatic visual cues are represented on different cortical surface representations that are capable of selectively attracting attention.

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Acetabular components were seated with 0.8 mm to 2 mm interference fits in reamed polyethylene bone substrate of two different densities (0.22 g/cm(3) and 0.45 g/cm(3)). Heat shock transcription factor-1 (HSF-1) was in a highly phosphorylated state in the antisense cell line before and after heat shock. The total number of published articles increased with each decade, but no articles were identified in the 1970s. Various properties of the core sequence, including membrane impairment ability and the seeding effect, have also been studied. This study, showing that swim therapy reduces neuropathic pain behavior in rats, provides a scientific rationale for clinicians to test the efficacy of exercise in the management of neuropathic pain.

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Prior beta-adrenergic stimulation enhances muscarinic negative inotropic responses, an effect that has been termed accentuated antagonism. The most striking change in spermatozoa incubated with cauda epididymal fluid was the addition of two glycopolypeptides of 32 and 33 kDa to the polypeptide maps of caput sperm cells. Exclusion criteria consisted of hemophilia or chronic conditions requiring anti-inflammatory medication. Although 15-deoxy-Delta12,14-prostaglandin J2 (15d-PGJ2) at micromolar concentrations significantly inhibited the production of TNF-alpha and IL-6, four other high affinity PPARgamma ligands failed to affect cytokine production.

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Non transfused children matched for age, sex, and social status with the subjects served as control. AMOVA indicated that majority of variation was confined to individuals within a population, with geographic grouping demonstrating lesser genetic differentiation as compared to linguistic clustering. Current professionally based education and training systems do not help to deliver this agenda. These observations support an interpretation of floral evocation as consisting, at least partially, of an early and qualitative change in gene expression. Binding of Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to Porphyromonas gingivalis fimbriae was characterized via a biomolecular interaction analysis system.

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Survival of Escherichia coli O157:H7 in soils from Jiangsu Province, China. Results of the combination of radiation-surgery in the treatment of cancer proximal stage I and II of the cervix uteri

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The surfaces were preadsorbed with plasma, serum, or plasma selectively depleted of fibronectin, vitronectin, or Von Willebrand factor, and platelet adhesion was measured. Cranial magnetic resonance imaging showed a smooth sella turcica, lacking the pituitary gland, and the absence of the normal sign of neurohypophysis. Moreover, the decrease of the DL was larger than one would expect from a simple model of information integration, which assumes that subjects improve their performance by averaging their percepts of the first intervals in the sequence. Significantly higher 24h mean blood lactate concentrations and lower total ketone bodies and glycerol concentrations were observed during treatment with human insulin.

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To evaluate outcome of red cell alloimmunized pregnancies treated with intravascular intrauterine blood transfusions. Ninety-nine pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. Independent prognostic factors included tumor stage, LN status (RFS and OS), and STSM status (OS). This study was undertaken to verify the prevalence of genital lesions associated to papillomavirus and sex, age and race distribution. A number of WASH-specific models and frameworks exist, yet with some limitations.

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Differences in prognosis of colorectal cancer patients based on the expression of sialyl Lewisa, sialyl Lewisx and sialyl Tn antigens in serum and tumor tissue. Eight novel dihydropridines analogs were synthesized using classic Hantzsch condensation reaction. Both indicated a remarkable improvement obtained when using the current algorithm to predict the contents of alpha-helix, beta-sheet, beta-bridge, 3(10)-helix, pi-helix, H-bonded turn, bend and random coil. Numerical simulation of the hemodynamic response to hemodialysis-induced hypovolemia.

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Roles of STAT3 in protein secretion pathways during the acute-phase response. The development of the Drosophila leg is a good model to study processes of pattern formation, cell death and segmentation.

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The levels of MMP8 and MMP9 were measured by ELISA on plasma samples obtained from 126 consecutive patients evaluated in the emergency department for suspected AAD. Study on the cytochemistry of isolated atractoplasma from spermatocytes in vitro

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The MC activation and the expression profiles of different components in the opioid signaling were demonstrated through routine histology and immunohistochemistry and Western blotting, in the superficial and deep muscle injury models. Current knowledge of pathogenesis, etiology and therapeutic possibilities Platelet and lactate dehydrogenase levels were the most useful analytical parameters in the follow-up. We studied whether these devices perform accurately and reliably under true mountain conditions. Here, we asked whether perikaryal modifications also occur when inferior olivary neurons enlarge their terminal fields to innervate supernumerary targets.

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Within 2 h of excretory urography 568 patients had add-on CT without using additional contrast medium. Hypoxia stimulates cell signaling in stellate cells, culminating in the rapid induction of VEGF and Flt-1 mRNA expression and VEGF secretion. There were 21 residents included in the program, with a mean age of 80 years. Tuberculosis is a major source of osteoarticular complications in northwestern Spain. Possibilities of post partum therapy are discussed in addition to obstetrical management.

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Determination of three drugs and their metabolites in saliva by ultra performance liquid chromatography-tandem mass spectrometry Some of these proteins are of outstanding interest in the biology and clinical management of this disease, such as CD44 and PARP1. By calculating the HpaII/ MspI peak ratio it is possible to evaluate the methylation level of normal and gastritis tissues. The dose planning predictability between departments did not appear to be significantly different for both the small and large breast phantoms. Low temperature route synthesis of SiC-Al2O3 hetero-structural nanofibers.

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Crystalcollagen relationships in bone as observed in the electron microscope. The purpose of this study is to determine and recommend the optimal radiation source according to breast size for tangential irradiation in breast conserving therapy.

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RamA, which controls expression of the MDR efflux pump AcrAB-TolC, is regulated by the Lon protease. On these bases, a clinical diagnosis of bilateral renal angiomyolipomas was made and surgical treatment of the left kidney was recommended because of its large size. The potyviruses infect not only dicotyledonous but also monocotyledonous plants.

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Aminophylline, widely used in the neonatal period, has been reported to be associated with necrotizing enterocolitis. Porcine epidemic diarrhea virus (PEDV) has caused devastating enteric disease in Korean pig farms since its first identification in 1992 in Korea. Effects of aortic nerve on hemodynamic response to obstructive apnea in sedated pigs.

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A case of congenital non-progressive cerebellar ataxia with pigmentary retinal degeneration, fiber type disproportion and hypercreatine kinasemia Comparison of techniques for coliform bacteria extraction from sediment of Xochimilco Lake, Mexico Modified autogenous latissimus breast reconstruction and the box top nipple.

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To evaluate the usefulness of magnetic resonance (MR) imaging and hydrogen 1 MR spectroscopy in the detection of brain involvement in patients with systemic lupus erythematosus (SLE) with or without neuropsychiatric symptoms. The exact activity profile depends on the particular analog and its route of administration. The clinical manifestations of stone disease are often more subtle in children when compared with the dramatic adult presentation. Isolation of the yeast calmodulin gene: calmodulin is an essential protein. Efficacy and tolerance of veralipride in the treatment of flushing in the menopause.

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Additional benefits of fish oils include improved endothelial function and better arterial compliance (elasticity). A decision-analytic model, using Markov process techniques, was designed to evaluate the lifetime clinical and economic consequences of treatment with letrozole compared with standard care with megestrol. Seasonal variation in serum testosterone, testicular measurements and semen characteristics in the collared peccary (Tayassu tajacu).

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Compared with healthy controls, patients with HBV-related decompensated cirrhosis showed significantly higher levels of TNF-alpha, IL-12, TGF-beta1, IL-17, and IL-8. Atlantoaxial rotatory fixation in a case of tubercular lymphadenitis. Disease severity should be taken into account when interpreting rates of VFI change over time.

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Comparison of antigen contents in co-cultures by an in situ immunoradiometric assay. An integrated approach, involving monitoring of phenological indicators along with expression profiling of the major vernalization regulator VRN1 orthologue, was followed. The current first-line psychopharmacologic treatment for PTSD is selective serotonin reuptake inhibitors (SSRIs). Monocytes from healthy adults are highly heterogeneous within and among individuals. Viral particles, averaging 45 nm in diameter, sometimes in crystalline arrays, were found in the nucleus of parotid epithelial cells.

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Vascular fluid shifts and endocrine responses to exercise in the heat. coli RNase H and analyzing 2,326 sequences of all HBV genotypes available in public databases and 958,000 sequences generated by means of ultradeep pyrosequencing of sequences from a homogenous population of 73 treatment-naive patients infected with HBV genotype D. Battle of the statins, or how the news media can change patient care. The results indicate that paper dust is the causative agent in hyperreactivity to newspapers.

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The efficacy of the combined procedure in involutional entropion surgery: a comparative study. Inhibiting proteasomes in human HepG2 and LNCaP cells increases endogenous androgen receptor levels. 3T3-L1 adipocytes or adipose-derived stem cells (ADSCs) that lacked Crif1 expressed lower levels of mtDNA-encoded OXPHOS subunits, and adipocyte differentiation was disrupted. It was previously demonstrated that SUM149PT human breast cancer cells show very high levels of cyclin E expression by western analysis and that they express a nonfunctional cyclin E ubiquitin ligase due to a mutation in the F-box protein hCdc4. The lipopolysaccharide-stimulated interleukin-6 and interleukin-8 production was markedly inhibited by MY4 or HTA125.

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Fructose-amino acids in liver: stimuli of amino acid incorporation in vitro. These images were printed in a water-soluble plastic on a three-dimensional (3D) printer to create biomodels. For backward perturbations, patients also had lower limits of stability, unrelated to TA strength or TS muscle tone.

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We investigated the role of RSV-specific IgE antibodies in the pathophysiology of virus-induced airway dysfunction in a mouse model. A heart transplant candidate with severe pulmonary hypertension and extremely high pulmonary vascular resistance. Previous research in this area has focused on the relative effects of cooperative versus competitive and individualistic learning situations upon peer relations and academic achievement. The document was developed from existing guidelines from a number of professional organizations including the American Academy of Pediatrics and the Society of Critical Care Medicine, a thorough review of the literature, and expert consensus. Spin-flop and antiferromagnetic phases of the ferromagnetic half-twist ladder compounds Ba3Cu3In4O12 and Ba3Cu3Sc4O12.

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In HPV-infected cells, a key regulator of p53 protein levels is the E6 oncoprotein. Paraneoplastic RS3PE is more frequently associated with solid tumors, in particular adenocarcinoma. Actual developments in European regulatory and health technology assessment of new cancer drugs: what does this mean for oncology in Europe? Use of double PCR in an experimental mode of HSV-1 infection of the facial nerve

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A total of 112 schizophrenia patients completed a neuropsychological evaluation. After sciatic nerve crush at 7 days of age, the corpuscles are mostly reinnervated with multiple axon terminals, each of them enclosed within a newly formed inner core.

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All genotype-sex-age cohorts demonstrated a reduced average lesion burden with CR. Allergic lung inflammation is caused by accumulation and activation of different leukocyte subsets, such as eosinophils and T lymphocytes, in the lung. A computed tomography (CT) scan revealed an acute subdural hematoma over the left temporoparietal region. Data were collected on actual time used by 1548 examinees for each of their 10 standardized patient encounters, for which a maximum of 15 minutes was allotted, but not required.

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Serum heat shock protein 47 levels are elevated in acute exacerbation of idiopathic pulmonary fibrosis. However, late during infection, MA, as part of Pr55, directs unspliced viral RNA augmentin generico equivalente de thevenin to the plasma membrane, the site of virus assembly.

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It encourages a respectful attitude toward the patient as a human being. Transhiatal esophagectomy in a furosemide medication side effects patient with aberrant right subclavian artery.

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The PI3K/AKT/mTOR and RAS/RAF/MEK/ERK pathways are known to interact with each other at several nodes, and mounting evidence suggests that dual blockade of both pathways may be required to achieve anticancer effects in certain contexts. The second example consists of the estimation of the posterior (spatial) distribution of a putative location. Only when amino-acid sequences of three loops in ACh-binding protein are changed to their 5-HT3A geramox and alcohol counterparts does ACh bind with low affinity characteristic of activatable receptors, and trigger opening of the ion pore. Mitochondrial DNA of Chlamydomonas reinhardtii: the DNA sequence of a region showing homology with mammalian URF2.

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We report on factors affecting the visualization of postmenopausal ovaries in the multicenter United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). The final model gave for the first time the complete rendering in silico of the cycling process calchek medicine hat following X-ray exposure, providing separate and quantitative measures of the dose-dependence of G1, S and G2M checkpoint activities in subsequent generations, reconciling known effects of ionizing radiations and new insights in a unique scenario.

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Our acyclovir dose in viral encephalitis recovery results shed light into the previously unknown cleavage of the sterane ring structure without oxygen. Together, these findings demonstrate a possible role for c-Jun in regulating p73 function and highlight the importance of the cooperativity between transcription factors in potentiating apoptosis. The proposed integrated host-pathogen interaction pathway model has accurately reflected the experimental evidences, which we have used for validation purpose. These results demonstrate true inattentional blindness for words and show that visual recognition wholly depends on attention even for highly familiar and meaningful stimuli at the center of gaze. Effect of liver-protective substances on content of pyridine coenzymes (DPN/DPNH2) in carbon tetrachloride poisoning in rats

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We will conduct subgroup analyses if possible according to severity/type of hearing disorder, age of identification, and type of hearing technology. The AASLD and EASL guidelines propos a diagnostic algorithm starting from the tumor size, whereas the APASL and Japanese guidelines recommend an algorithm starting from arterial tumor vascularity (hyper- or hypovascular in the arterial phase). Periodontally reduced dentitions are associated with an increased load on periodontal tissue. These results and several years of clinical experiences in adhesive clindamycin and differin gel denture work establish the usefulness of combining electrolytically corroded Wiron 88 and Superbond. Immune responses mediated by IgE are important in the pathogenesis of allergic asthma.

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