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Saitan (Telmisartan)
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Telmisartan

To investigate the effect of Saitan on the protein and gene expression of angiotensin-converting enzyme-2 (ACE2) in human umbilical vein endothelial cells (HUVECs). These results indicate that Saitan prevents MGO-induced apoptosis by inhibiting caspase-3 activation, which might explain at least in part the beneficial effects of telimisartan against diabetes-related cardiovascular diseases.

Other names for this medication:
Telmisartan, Micardis, Kinzalkomb, Kinzalmono, Mitosan, Pritor, Pritorplus, Saitan, Telma, Telpres, Telsan, Twynsta,

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Saitan is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.

Saitan is also used to lower the risk of heart attacks or stroke in patients 55 years of age and older who have diabetes or heart problems.

Saitan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to tighten. As a result, Saitan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

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Mel-2) cell lines was biologically functional and was able to biotinylate secretary target protein (on specific lysine residue present on the BSP tag). In Studies 3-5, individuals in a prevention focus, but not individuals in a promotion focus, exhibited a reluctance to exchange currently possessed objects (i.e., endowment) or previously possessed objects. We sought to investigate the mechanism of action of aspirin on IgE-mediated histamine release. Many colleges assess criminal histories during the admissions process, in part, to address violence on campus. On the other hand, the survival rates of the mice were followed daily.

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Our results indicate that the aneuploid tumor cell lines have an increased sensitivity to these reagents and a delay in aster formation and microtubule regrowth. Previous studies have shown that the immune response to trivalent oral poliovirus vaccine (OPV) varies widely from country to country.

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This variant probably corresponds to a form that has been purified from leech heads but differs in amino acid sequence from the hirudin purified from whole leeches. Current status of prediction of drug disposition and toxicity in humans using chimeric mice with humanized liver. Our experience with the modified rectal bladder in children with considerable follow-up periods is reported herein.

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Electronic survey of student pharmacists between March and October 2011. This study aimed to compare the arthroscopic patch graft procedure and partial repair for irreparable large or massive rotator cuff tears (RCTs) in shoulders with low-grade fatty degeneration of the infraspinatus (stage 1 or 2 according to Goutallier et al.) in terms of the functional and structural outcomes.

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mirabilis, the Ery-protective effect was maintained in the course of several generations. Focusing was performed with a heavy-ion scanning high-precision magnetic quadrupole triplet microprobe. The basic criterion was the sensitivity of INT to the analysis parameters, especially the data window.

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Characterization of factors regulating lamina-specific growth of thalamocortical axons. Treatment of autoimmune myasthenia frequently involves long-term exposure to immunosuppressants, including azathioprine. However, low levels of viral RNA were detected in the blood of vaccinated lambs shortly after challenge infection.

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The conductive properties of single DNA molecules studied by torsion tunneling atomic force microscopy. The purpose of this study was to evaluate the MRI characteristics of the suprapatellar fat-pad, determine the prevalence and pattern of suprapatellar fat-pad edema, and correlate the findings with the presence of anterior knee pain, patellofemoral malalignment, and patellofemoral joint osteoarthritis. The diagnosis of pheochromocytoma is established more frequently in recent years due to better diagnostic possibilities. In patients with liver diseases, hemostasis tests can be required to evaluate the degree of hepatocellular failure, the severity of hemostasis disorders manifesting as bleeding, or the bleeding risk before an invasive procedure.

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Such models are displayed in 3-D and may further analysed utilizing interactive 3-D computer graphics. Implications for understanding the role of social support in attenuating the effects of physical disability in older adults are discussed.

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REBUILD: an orthopedic trauma support group and community outreach program. Regeneration of a plate is much faster in relation to the growth in length of the bone in the rabbit than in the pig. Extending the serum half-life of G-CSF via fusion with the domain III of human serum albumin.

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Breast milk collection and storage practices among mothers of hospitalized neonates. Correlation between low back pain and the loss of LL in the treatment of low-grade lumbar degenerative spondylolisthesis has seldom been reported.

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Disseminated intravascular coagulation and purpura fulminans in a patient with Candida sepsis. A Geographic Information System (GIS) was established aiming to conduct a series of remote sensing studies based on digital image processing and analysis from Landsat TM and panchromatic Spot.

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We determined whether the addition of 6 laterally directed cores to the traditional sextant prostate biopsy affects the performance of percent fPSA. We report here identification of a functional transposase of Tol2 that is capable of catalyzing its transposition in the germ line of zebrafish Danio rerio. A Scottish tertiary referral center for investigation of photodermatosis. The Prerequisite Curriculum (PRC) contains 75 segments organized with textbook and case-based navigational systems.

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Safety and efficacy of low-dose methotrexate for pediatric patients with steroid-refractory acute graft-versus-host disease after hematopoietic stem cell transplantation. Multidrug resistance, especially multidrug efflux mechanisms that extrude structurally unrelated cytotoxic compounds from the cell by multidrug transporters, is a serious problem and one of the main reasons for the failure of therapeutic treatment of infections by pathogenic microorganisms as well as of cancer cells. PD153035, at nanomolar concentrations, inhibited autophosphorylation of the EGF receptor induced by EGF stimulation and the inhibition occurred in a dose-dependent manner.

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A prospective cohort study was conducted, in which 7076 individuals were interviewed with the Composite International Diagnostic Interview Schedule at baseline and 1 and 3 years later. The practical considerations inherent in this type of analysis are highlighted, as well as the use of this type of data to inform agency human resource strategies. The organelles observed in the sequestered material included multilamellar bodies, which have not been reported earlier in these organelles. To report the surgical injury of a tortuous vertebral artery resulting from rheumatoid arthritis and to stress the value of cross-sectional imaging in identifying this anomaly before surgery in these patients. Prophylactic oophorectomy in the treatment of carcinoma of the breast.

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Behavioral interventions for improving contraceptive use among women living with HIV. In this study using the Dual-Luciferase reporter assay, we demonstrate that interaction of the T-cell line Jurkat with SFCs results in a higher activity of the APN/CD13 myeloid promoter in T cells. Endovascular stroke therapy has revolutionized the management of patients with acute ischemic stroke in the last decade and has facilitated the development of sophisticated stroke imaging techniques and a multitude of thrombectomy devices.

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When time from blood sampling to diagnosis of the case was considered, it could be shown that the protective effect of high serum selenium concentrations was restricted to the last (less than 7) years prior to the diagnosis of thyroid cancer. Tumor growth was monitored as long as 140 days by external caliper measurements. In a third co-expression in which the modified HBc helper lacked aa 76-85 in the MIR, the incorporation level of HBc-preS fusion into the particles was noticeably lower. The AIGISRx envelope significantly lowered the risk of CIED infection. Arteriography of the uterine artery: its value in the diagnosis of uterine fibromyoma, tubal pregnancy, adnexal tumour, and placental site localization in cases of intra-uterine pregnancy.

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This editing mechanism in immature T cells parallels that which occurs in immature B cells, and has important implications for understanding positive and negative selection signaling in the thymus, and the limits of self-tolerance. Thrombin-stimulated calcium uptake is altered in platelets from spontaneously hypertensive rats. Reversible addition of the OH radical to p-cymene in the gas phase: kinetic analysis assuming formation of a single adduct.

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The specialty of allergy and immunology has seen the second largest increase in the popularity of CAM (second only to practitioners who treat lower back pain). Light optic and electron microscopic studies were made of endomyocardial biopsies from the right ventricle of 8 patients who had undergone orthotopic transplantation of the heart 7-14 years ago. After sequencing, the likely exon/intron structure was determined by comparison to genomic sequence. There is now a good deal of evidence to suggest that endogenous oxytocin may also be involved in this process, probably through a stimulatory action on uterine prostaglandin synthesis.

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PhoA fusions, deletional mutagenesis, and N-terminal amino acid sequencing established that the signal for Hia export from the cytoplasm resides in the first 49 amino acids, including a 24-amino-acid stretch with striking similarity to the N terminus of a number of proteins belonging to the autotransporter family. In order to systematically study visual responses in freely behaving animals, an unobtrusive system for monitoring eye-in-orbit position in real time is essential. Patients with measurable inoperable or metastatic colorectal cancer were randomized to receive weekly FU 500 mg/m2 by intravenous (IV) bolus combined with high-dose FA 500 mg/m2 (group A) or low-dose FA 20 mg/m2 (group B) by 2-hour infusion. Furthermore, treatment of Xenopus tadpoles with exogenous RA led to an expansion of the pancreatic field. We performed a meta-analysis including 28 clinical trials on the use of somatostatin (12 studies), octreotide (10 studies), and gabexate mesilate (6 studies) after ERCP.

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Effects of HSP90 inhibitor 17-AAG on cell cycle and apoptosis of human gastric cancer cell lines SGC-7901 Using in situ hybridization and the avidin biotin-complex (ABC) immunoperoxidase method, we have demonstrated the presence of TNF mRNA in the cytoplasm and TNF protein in the granules of individual human basophil/mast cells. Based on their infectivity, about 120 sera were classified in three groups. A number of variables affect the penetration depth of a Nd:YAG laser, some of which are difficult to control with precision in an endoscopic setting.

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Effect of feeding silages from corn hybrids selected for leafiness or grain to lactating dairy cattle. Despite improvements in surgical techniques and antimicrobial therapies, prosthetic aortic graft infections remain a clinical problem. Data on the cost-efficacy of the two triptans were derived from a recently published Italian, multicenter, randomized, double-blind, cross-over patient gelnique reviews side effects preference study, comparing frovatriptan versus rizatriptan. However, little is known about the relationship of O(6)MGMT to the characteristics of melanoma. A 40 years old male, known case of tetralogy of Fallot, was operated in infancy in abroad, presented with a rapid enlargement of right breast over 5 - 6 weeks.